Scientists have made a bone-repairing material out of wool

Dr Sherif Elsharkawy holds a human skull. Photo: King's College London.

Scientists at King's College London have shown that material made from ordinary wool can help repair damaged bone. This is important because wool is often left as an agricultural waste and its protein, keratin, could be the basis for new medical materials.

This is still about laboratory tests and animal experiments, not about use in patients.

Details

The researchers used keratin, a tough natural protein found in wool, hair and nails. They used it to make special membranes, that is, thin frameworks that should guide the growth of new bone tissue.

The material was first tested on human bone cells in the laboratory. The cells on such membranes survived and showed signs of normal bone formation.

The membranes were then tested on rats with skull bone defects that would not heal completely on their own. Over several weeks, the scientists watched as the keratin material helped new bone grow through the damaged area.

Now collagen membranes are often used in regenerative medicine. They are considered the standard but have limitations: they may not be strong enough, degrade too quickly, and are expensive to produce.

In the experiment, collagen membranes yielded more bone tissue by volume. But keratin membranes made from wool formed a more ordered and structurally similar tissue to healthy bone. In addition, the material incorporated well into the surrounding tissue and remained stable during healing.

Why it matters

The study shows that wool may not just be a waste product, but a raw material for medical materials.

Such keratin membranes could potentially be used in dentistry, oral and maxillofacial surgery and other areas where bone tissue needs to be rebuilt.

The main advantage is the combination of medical function and sustainability: wool is a renewable material, and agriculture often produces it in abundance.

But it's important to emphasise: this is not yet a clinic-ready technology. Further trials are needed to understand the safety, durability and effectiveness of the material in humans.

Background

Keratin has long been seen as a promising biomaterial. It is biocompatible, degrades in the body and could serve as the basis for materials on which cells grow. Previously, keratin structures have been studied for tissue repair, drug delivery and wound healing.

A new study takes the next step: showing that keratin from wool can support bone regeneration in a living organism.

Source

The study was conducted by a team at King's College London. In it, keratin membranes from wool were tested on human bone cells and in a preclinical model of bone repair.